Ofev® (nintedanib esilate)
Progressive Pulmonary Fibrosis (PPF)
Progressive Pulmonary Fibrosis (PPF)
Pulmonary Fibrosis (PF) is a condition in which the tissue in the lungs becomes thickened, stiff and permanently scarred. This scarring is called fibrosis. In PPF this scarring of the lung tissue has shown signs of getting worse. As a result, less oxygen is able to enter the bloodstream and it becomes difficult to breathe deeply. This is why patients may feel out of breath during daily activities. However, the symptoms of PPF may be different for each person.
Key medical terms:
- Progressive: getting worse over time
- Pulmonary: anything related to the lungs
- Fibrosis: the formation of scar tissue
PPF may be managed in a number of ways. These include medical treatment, pulmonary rehabilitation to help manage symptoms, supplemental oxygen to keep oxygen levels at a healthy level or lung transplantation.
What is Ofev®?
Ofev® is part of a group of medicines known as 'anti-fibrotics' and contains the active ingredient nintedanib. It is used in the treatment of Idiopathic Pulmonary Fibrosis or other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype.
Possible side effects
The most frequent side effects which may be experienced when taking Ofev® (nintedanib) include diarrhoea, nausea and vomiting, abdominal pain, decreased appetite, weight loss and abnormal liver test results. Please refer to the patient information leaflet about other possible side effects.
Where can I find more information?
Patient Information Leaflet
The Patient Information Leaflet is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using this medicine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
If you are in the United Kingdom, click the below link to access this information
Patient Information Leaflet
Summary of Product Characteristics
The Summary of Product Characteristics tells healthcare professionals, such as doctors, pharmacists and nurses, how to prescribe and use this medicine correctly. The information in the Patient Information Leaflet and Summary of Product Characteristics are not intended to replace the opinion of a healthcare professional.
If you are in the United Kingdom, click the below link to access this information
NP-GB-103761 | December 2024
